A novel mouse model reproducing frontal alterations related to the prodromal stage of dementia with LEWY bodies

This study demonstrates that pathophysiological impairment of the FC with concomitant DH preservation is observed at an early stage of DLB, and that the mThy1-hSNCA mouse model parallels some markers of this pathology.

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Publication Details

Journal
Neurobiology of Disease
Published
2024-09-20
DOI
https://doi.org/10.1016/j.nbd.2024.106676
Primary Topic
Olfactory and Sensory Function Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

A novel mouse model reproducing frontal alterations related to the prodromal stage of dementia with LEWY bodies

Olivier Bousiges, Anne‐Laurence Boutillier, Anne Pereira de Vasconcelos, Brigitte Cosquer et al.
Neurobiology of Disease
Olfactory and Sensory Function Studies
article

A novel mouse model reproducing frontal alterations related to the prodromal stage of dementia with LEWY bodies

Olivier Bousiges, Anne‐Laurence Boutillier, Anne Pereira de Vasconcelos, Brigitte Cosquer, Iris Grgurina, Aline Stéphan, Estelle Schueller, Karine Mérienne, Frédéric Blanc, Chantal Mathis, Noémie Penaud, Jean-Christophe Cassel, Élodie Panzer
article en

Abstract

This study demonstrates that pathophysiological impairment of the FC with concomitant DH preservation is observed at an early stage of DLB, and that the mThy1-hSNCA mouse model parallels some markers of this pathology.

Neurobiology of DiseaseVol. 201
Centre National de la Recherche Scientifique (FR), Laboratoire de Neurosciences Cognitives et Adaptatives (FR), Université de Strasbourg (FR)
Gender equality
Openalex Percentile: Top 86%
Olfactory and Sensory Function Studies
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A novel mouse model reproducing frontal alterations related to the prodromal stage of dementia with LEWY bodies — Olivier Bousiges, Anne‐Laurence Boutillier, et al. · Neurobiology of Disease (2024) | TGRS Research Map | TGRS