Novel mechanisms of intestinal flora regulation in high-altitude hypoxia
The study reveals that firmicutes, through the inhibition of the HIF-1α/glycolysis pathway, mitigate Mψ polarization, thereby alleviating intrinsic mucosal barrier injury in high-altitude hypoxia.
Authors
- Dejun Cui (ORCID: https://orcid.org/0000-0002-3653-3058)
- Fang Yan (ORCID: https://orcid.org/0000-0003-4959-2433)
- Yun-han Yang
- Shimin Wu
- Wenqiang Yuan
Institutions
- Guiyang Medical University (CN)
- Guizhou University (CN)
- Zunyi Medical University (CN)
- Guizhou Provincial People's Hospital (CN)
Publication Details
- Journal
- Heliyon
- Published
- 2024-09-20
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e38220
- Citations
- 6
- Primary Topic
- High Altitude and Hypoxia
- Type
- article
- Field-Weighted Citation Impact
- 3.30