Macrostructural Brain Abnormalities in Spinal Muscular Atrophy
Individuals with SMA have higher rates of macrostructural brain abnormalities than their neurotypical peers, suggesting CNS involvement in SMA. Understanding changes in the brain architecture of the SMA population can inform the development of adjunct therapies targeting the CNS and potentially guide rehabilitation strategies.
Authors
- Christine Saint‐Martin (ORCID: https://orcid.org/0000-0002-3632-7502)
- Roberta La Piana (ORCID: https://orcid.org/0000-0002-4207-5065)
- Émilie Groulx‐Boivin (ORCID: https://orcid.org/0000-0001-6459-271X)
- Amalia Floer
- Maryam Oskoui (ORCID: https://orcid.org/0000-0003-1042-0108)
- Helen L. Carlson (ORCID: https://orcid.org/0000-0002-5788-0542)
- Adam Kirton (ORCID: https://orcid.org/0000-0001-5209-3374)
- Jean K. Mah (ORCID: https://orcid.org/0000-0002-5795-9955)
- Andrea Oliveira-Carneiro
Institutions
- Montreal Children's Hospital (CA)
Publication Details
- Journal
- Neurology Genetics
- Published
- 2024-09-20
- DOI
- https://doi.org/10.1212/nxg.0000000000200193
- Citations
- 4
- Primary Topic
- Neurogenetic and Muscular Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 1.75