Determining Clinicopathologic Factors That Influence Treatment in Advanced Breast Cancer in Argentina After CDK4/6 Inhibitors

In our study, treatment decisions reflected the current algorithm incorporated in our clinical guidelines, and prior treatment response was the most relevant factor to determine 2L treatment decision. Menopausal status interacted with the subsequent therapy efficacy in this setting. Hence, we consider that menopausal status should be routinely evaluated in the subgroup analysis of clinical trials.

Authors

Institutions

Publication Details

Journal
JCO Global Oncology
Published
2024-09-01
DOI
https://doi.org/10.1200/go.24.00056
Primary Topic
Advanced Breast Cancer Therapies
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Determining Clinicopathologic Factors That Influence Treatment in Advanced Breast Cancer in Argentina After CDK4/6 Inhibitors

Carolina Almada, R. Villarreal Gonzalez, A. Guercovich, A. Mainella et al.
JCO Global Oncology
Advanced Breast Cancer Therapies
article

Determining Clinicopathologic Factors That Influence Treatment in Advanced Breast Cancer in Argentina After CDK4/6 Inhibitors

Carolina Almada, R. Villarreal Gonzalez, A. Guercovich, A. Mainella, Maribel A. Lutteral, Gonzalo Gomez-Abuin, Luciano Cermignani, Natalia Ayala, Cristian Micheri, M.C. Riggi, Melina Winocur, Ana Carolina Ituarte, Federico Waisberg, Rosa Penayo, A Mazzotta, Pablo Mandó, M.L. Casalnuovo, S. Cinquini, Janeth Lara Alcántara, Pamela Llugdar, Naima Kassis, L. Gonzalez Mattos
article en

Abstract

In our study, treatment decisions reflected the current algorithm incorporated in our clinical guidelines, and prior treatment response was the most relevant factor to determine 2L treatment decision. Menopausal status interacted with the subsequent therapy efficacy in this setting. Hence, we consider that menopausal status should be routinely evaluated in the subgroup analysis of clinical trials.

JCO Global OncologyVol. 10(10)
Hospital Italiano de Buenos Aires (AR), Instituto Alexander Fleming (AR), Instituto Oncológico de Córdoba (AR), Centro de Educación Médica e Investigaciones Clínicas Norberto Quirno (AR), Hospital Alemán (AR), Hospital Británico de Buenos Aires (AR), Instituto de Oncología de Rosario (AR), Hospital General de Agudos Dr. TEODORO ALVAREZ (AR)
Good health and well-being
Openalex Percentile: Top 71%
Advanced Breast Cancer Therapies
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.