Association of Neurogranin and BACE1 With Clinical Cognitive Decline in Individuals With Subjective Cognitive Decline
Our findings suggest that CSF neurogranin and BACE1 begin to change in the preclinical stage of AD and they are associated with clinical progression in individuals with SCD.
Authors
- Emrah Düzel (ORCID: https://orcid.org/0000-0002-0139-5388)
- Silka Dawn Freiesleben (ORCID: https://orcid.org/0000-0002-2141-8671)
- Jens Wiltfang (ORCID: https://orcid.org/0000-0003-1492-5330)
- Ayda Rostamzadeh (ORCID: https://orcid.org/0000-0001-5189-134X)
- Lukas Preis (ORCID: https://orcid.org/0000-0001-7601-6410)
- Robert Perneczky (ORCID: https://orcid.org/0000-0003-1981-7435)
- Annika Spottke (ORCID: https://orcid.org/0000-0001-9854-2972)
- Oliver Peters (ORCID: https://orcid.org/0000-0003-0568-2998)
- Stefan Johannes Teipel (ORCID: https://orcid.org/0000-0002-3586-3194)
- Niels Hansen (ORCID: https://orcid.org/0000-0001-5785-9594)
- Frederic Brosseron (ORCID: https://orcid.org/0000-0003-3137-7516)
- Alfredo Ramı́rez (ORCID: https://orcid.org/0000-0003-4991-763X)
- Boris‐Stephan Rauchmann (ORCID: https://orcid.org/0000-0003-4547-6240)
- Christoph Laske (ORCID: https://orcid.org/0009-0009-3434-936X)
- Luca Kleineidam (ORCID: https://orcid.org/0009-0006-3309-6856)
- Michael Ewers (ORCID: https://orcid.org/0000-0001-5231-1714)
- Michael Wagner (ORCID: https://orcid.org/0000-0003-2589-6440)
- Katharina Büerger (ORCID: https://orcid.org/0000-0002-5898-9953)
- Klaus Fließbach (ORCID: https://orcid.org/0000-0002-0183-7510)
- Enise I. Incesoy (ORCID: https://orcid.org/0000-0003-2014-4098)
- Josef Priller (ORCID: https://orcid.org/0000-0001-7596-0979)
- Steffen Wolfsgruber (ORCID: https://orcid.org/0000-0002-3962-3219)
- Frank Jessen (ORCID: https://orcid.org/0000-0003-1067-2102)
- Daniel Janowitz (ORCID: https://orcid.org/0009-0003-4090-547X)
- Ingo Kilimann (ORCID: https://orcid.org/0000-0002-3269-4452)
- Anja Schneider (ORCID: https://orcid.org/0000-0001-9540-8700)
- Michael T. Heneka (ORCID: https://orcid.org/0000-0003-4996-1630)
- Slawek Altenstein (ORCID: https://orcid.org/0000-0003-2753-5999)
- Luisa‐Sophie Schneider (ORCID: https://orcid.org/0000-0001-5822-1744)
- Wenzel Glanz (ORCID: https://orcid.org/0000-0002-5865-4176)
- Matthias H. Munk (ORCID: https://orcid.org/0000-0002-5339-4045)
- Eike Spruth
- Melina Stark (ORCID: https://orcid.org/0009-0005-3812-023X)
- Nina Roy‐Kluth
- Xiao Wang (ORCID: https://orcid.org/0000-0002-6811-2733)
- Doreen Göerß
Institutions
- Humboldt-Universität zu Berlin (DE)
Publication Details
- Journal
- Neurology
- Published
- 2024-09-20
- DOI
- https://doi.org/10.1212/wnl.0000000000209806
- Citations
- 1
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.39
Funders
- Deutsches Zentrum für Neurodegenerative Erkrankungen