Multiple sporadic schwannomas in a previously radiated field

Peripheral nerve sheath tumors are a heterogenous group of predominantly benign tumors of neurogenic origin that arise outside of the central nervous system and include schwannomas and neurofibromas. These tumors often occur sporadically, however multiple lesions are generally associated with genetic syndromes such as neurofibromatosis (type 1 and 2) and schwannomatosis, and occasionally these tumors and their malignant variations are associated with a history of radiation treatment. Multiple benign schwannomas in an irradiated field have seldom been reported in the literature. We describe a case of a 49-year-old male with a history of right sided irradiated testicular cancer who presented with 2 histologically confirmed benign schwannomas in the right pelvic wall and right psoas muscle.

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Publication Details

Journal
Radiology Case Reports
Published
2024-09-20
DOI
https://doi.org/10.1016/j.radcr.2024.09.051
Primary Topic
Neurofibromatosis and Schwannoma Cases
Type
article
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article

Multiple sporadic schwannomas in a previously radiated field

Nicholas Matthew Bernthal, Scott D. Nelson, Jeffrey Rosenthal, Chukwuemeka Chukwubuikem Okoro et al.
Radiology Case Reports
Neurofibromatosis and Schwannoma Cases
article

Multiple sporadic schwannomas in a previously radiated field

Nicholas Matthew Bernthal, Scott D. Nelson, Jeffrey Rosenthal, Chukwuemeka Chukwubuikem Okoro, Naomi E. Walker, Varand Ghazikhanian
article en

Abstract

Peripheral nerve sheath tumors are a heterogenous group of predominantly benign tumors of neurogenic origin that arise outside of the central nervous system and include schwannomas and neurofibromas. These tumors often occur sporadically, however multiple lesions are generally associated with genetic syndromes such as neurofibromatosis (type 1 and 2) and schwannomatosis, and occasionally these tumors and their malignant variations are associated with a history of radiation treatment. Multiple benign schwannomas in an irradiated field have seldom been reported in the literature. We describe a case of a 49-year-old male with a history of right sided irradiated testicular cancer who presented with 2 histologically confirmed benign schwannomas in the right pelvic wall and right psoas muscle.

Radiology Case ReportsVol. 19(12)
UCLA Health (US)
Openalex Percentile: Top 75%
Neurofibromatosis and Schwannoma Cases
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Multiple sporadic schwannomas in a previously radiated field — Nicholas Matthew Bernthal, Scott D. Nelson, et al. · Radiology Case Reports (2024) | TGRS Research Map | TGRS