Management and follow-up strategies for patients with head and neck paraganglioma
Patients without SDHx-related HNPGLs require long-term follow-up due to high prevalence of RD with imaging largely restricted to head-neck regions. As carotid-body HNPGLs have the highest metastatic risk among sporadic tumors, radical treatment with frequent follow-up is suggested until population-based data are available. Importantly, patients with SDHx-related HNPGLs might benefit from early radical treatment when tumors are still small to reduce metastatic risk.
Authors
- Christina Pamporaki (ORCID: https://orcid.org/0000-0003-0772-1604)
- Hanna Remde (ORCID: https://orcid.org/0000-0002-3499-5910)
- Graeme Eisenhofer (ORCID: https://orcid.org/0000-0002-8601-9903)
- Andrzej Januszewicz (ORCID: https://orcid.org/0000-0002-1831-250X)
- Henri Timmers (ORCID: https://orcid.org/0000-0002-1208-5748)
- Mercedes Robledo (ORCID: https://orcid.org/0000-0001-6256-5902)
- Karel Pacák (ORCID: https://orcid.org/0000-0002-3541-3767)
- Svenja Nölting (ORCID: https://orcid.org/0000-0002-7064-590X)
- Susan Richter (ORCID: https://orcid.org/0000-0002-3549-2477)
- Henricus P. M. Kunst (ORCID: https://orcid.org/0000-0003-1162-6394)
Institutions
- National Institutes of Health (US)
- Radboud University Nijmegen (NL)
- University of Zurich (CH)
- University of Würzburg (DE)
- University Medical Center (US)
- Radboud University Medical Center (NL)
- Maastricht University (NL)
- University Hospital of Zurich (CH)
- Centre for Biomedical Network Research on Rare Diseases (ES)
- Centro de Investigación Biomédica en Red (ES)
- Universitätsklinikum Würzburg (DE)
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (US)
- University Hospital Carl Gustav Carus (DE)
- Technische Universität Dresden (DE)
- Ludwig-Maximilians-Universität München (DE)
Publication Details
- Journal
- European Journal of Endocrinology
- Published
- 2024-09-20
- DOI
- https://doi.org/10.1093/ejendo/lvae113
- Citations
- 7
- Primary Topic
- Adrenal and Paraganglionic Tumors
- Type
- article
- Field-Weighted Citation Impact
- 4.01
Funders
- Deutsche Forschungsgemeinschaft
- Technische Universität Dresden
- National Institutes of Health