Integrative analysis of the efficacy and pharmacological mechanism of Xuefu Zhuyu decoction in idiopathic pulmonary fibrosis via evidence-based medicine, bioinformatics, and experimental verification
The effectiveness of XFZYD on IPF has been substantiated through evidence-based medicine. The pharmacological mechanism of XFZYD for IPF treatment involves a complex interplay of various compounds and targets, with quercetin exerting pronounced impacts on JUN and PTGS2 proteins.
Authors
- Qingqing Xia (ORCID: https://orcid.org/0000-0001-5287-0639)
- Weilong Jiang (ORCID: https://orcid.org/0000-0001-8416-6080)
- Haibing Hua (ORCID: https://orcid.org/0000-0001-9346-9972)
- Cong Wang (ORCID: https://orcid.org/0000-0001-9953-7518)
- Huizhe Zhang (ORCID: https://orcid.org/0000-0002-6378-6982)
- Chenjing Zhu (ORCID: https://orcid.org/0000-0001-8798-6367)
- Yufeng Zhang (ORCID: https://orcid.org/0000-0002-3154-7979)
- Xiaodong Hu (ORCID: https://orcid.org/0009-0001-1001-1358)
- Xiangjin Cheng
- Jian Liu (ORCID: https://orcid.org/0000-0003-4362-5273)
Institutions
- Nanjing University of Chinese Medicine (CN)
- Soochow University (CN)
- Jiangyin People's Hospital (CN)
- Jiangyin Traffic Planning Survey & Design Institute (China) (CN)
- Yancheng Third People's Hospital (CN)
- Yancheng Second People's Hospital (CN)
- Fourth People's Hospital of Changzhou (CN)
Publication Details
- Journal
- Heliyon
- Published
- 2024-09-20
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e38122
- Citations
- 1
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 0.42
Funders
- Wuxi Health and Family Planning Commission