The Association between Aminoglycoside Exposure and Ototoxicity in Children with Cystic Fibrosis

As AG ototoxicity occurs primarily at high frequencies, EHF-PTA is important in early detecting ototoxicity. EHF-PTA and DPOAE detected ototoxicity in some patients with normal PTA results. All pwCF with a history of AG exposure should be evaluated for hearing loss since symptoms may only be noticed in the late period.

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Publication Details

Journal
Respiration
Published
2024-09-19
DOI
https://doi.org/10.1159/000541447
Primary Topic
Hearing, Cochlea, Tinnitus, Genetics
Type
article
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article

The Association between Aminoglycoside Exposure and Ototoxicity in Children with Cystic Fibrosis

M. Kalyoncu, Pınar Ata, Ayça Çiprut, Ahmet Ataş et al.
Respiration
Hearing, Cochlea, Tinnitus, Genetics
article

The Association between Aminoglycoside Exposure and Ototoxicity in Children with Cystic Fibrosis

M. Kalyoncu, Pınar Ata, Ayça Çiprut, Ahmet Ataş, Nesibe Karasu, Halide Çetin Kara, Saniye Girit, Özge Gedik Toker, Ali Cemal Yumuşakhuylu, Merve Selçuk, Melda Acar, Yasemi̇n Gökdemi̇r, Şeyda Karabulut, Fazi̇let Karakoç, Mürüvvet Yanaz, Erkan Çakır, Abdülhamit Çollak, Özge Meral, Burcu Uzunoğlu, Nilüfer Bal, Yetkin Ayhan, Ayşe Ayzıt Kılınç Sakallı, Ela Erdem Eralp, Bulent Taner Karadag, Yesim Oruc, Fatma Toktas, Cansu Yılmaz Yeğit, Remzi Doğan, Pınar Ergenekon, Hale Molla Kafi, Nezafet Ozturk Akar, Aynur Guliyeva, Gamze Taştan, Emine Deniz Gozen Tan
article en

Abstract

As AG ototoxicity occurs primarily at high frequencies, EHF-PTA is important in early detecting ototoxicity. EHF-PTA and DPOAE detected ototoxicity in some patients with normal PTA results. All pwCF with a history of AG exposure should be evaluated for hearing loss since symptoms may only be noticed in the late period.

RespirationVol. 104(1)
Bezmiâlem Vakıf Üniversitesi (TR), Istanbul University-Cerrahpaşa (TR), Istinye University (TR), Istanbul Medeniyet University (TR), Istanbul University (TR), Marmara University (TR)
Good health and well-being
Openalex Percentile: Top 86%
Hearing, Cochlea, Tinnitus, Genetics
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