Early-Life Risk Factors for Carotid Intima-Media Thickness and Carotid Stiffness in Adolescence
In this cohort study of 232 participants, early-life growth parameters, and particularly abdominal VAT development, were associated with a higher cIMT and carotid stiffness in adolescence. These findings suggest that assessment of adipose tissue development during childhood can aid characterization of lifetime risk trajectories and tailoring of cardiovascular prevention and risk management strategies.
Authors
- Sabine E.I. van der Laan (ORCID: https://orcid.org/0000-0002-4632-7821)
- Cornelis K. van der Ent (ORCID: https://orcid.org/0000-0002-2501-4121)
- Roderick P Venekamp (ORCID: https://orcid.org/0000-0002-1446-9614)
- Sanne L. Nijhof (ORCID: https://orcid.org/0000-0003-1538-5014)
- Isabelle A. van der Linden
- Henk S. Schipper (ORCID: https://orcid.org/0000-0003-1997-8060)
- Rozan Roodenburg
Institutions
- Utrecht University (NL)
- University Medical Center Utrecht (NL)
- Erasmus MC - Sophia Children’s Hospital (NL)
- Wilhelmina Children's Hospital (NL)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2024-09-20
- DOI
- https://doi.org/10.1001/jamanetworkopen.2024.34699
- Citations
- 11
- Primary Topic
- Birth, Development, and Health
- Type
- article
- Field-Weighted Citation Impact
- 12.20