Genetically predicted N-Acetyl-L-Alanine mediates the association between CD3 on activated and secreting Tregs and Guillain-Barre syndrome
In conclusion, our study identified a causal relationship between the level of CD3 on activated & secreting Tregs and GBS by genetic means, with a considerable proportion of the effect mediated by ALA. In clinical practice, thus providing guidance for future clinical research.
Authors
- Yasuo Ding
- Zehao Liu (ORCID: https://orcid.org/0000-0002-4994-0568)
- Qi Lyu
- Lianlian Zhang (ORCID: https://orcid.org/0000-0003-0966-4228)
Institutions
- Xuzhou Medical College (CN)
- Nantong University (CN)
- Yancheng First People's Hospital (CN)
- The Affiliated Taizhou People's Hospital of Nanjing Medical University (CN)
- Taizhou University (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Frontiers in Neuroscience
- Published
- 2024-09-20
- DOI
- https://doi.org/10.3389/fnins.2024.1398653
- Citations
- 3
- Primary Topic
- Hereditary Neurological Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.80