Novel Treatment Strategies for Low-Risk Metastatic Castration-Sensitive Prostate Cancer

The Canazawa classification differentiated the prognosis of mCSPC patients more clearly. A PSA reduction rate of <95% at 12 w after starting ADT in low-risk, low-volume patients of all risk classifications was significantly shorter than the TTCR. We propose a new treatment strategy, in which patients with low-risk mCSPC are treated with ADT and switched to ARSIs based on the rate of PSA reduction at 12 w.

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Publication Details

Journal
Cancers
Published
2024-09-19
DOI
https://doi.org/10.3390/cancers16183198
Citations
5
Primary Topic
Prostate Cancer Treatment and Research
Type
article
Field-Weighted Citation Impact
2.09
Controls
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article

Novel Treatment Strategies for Low-Risk Metastatic Castration-Sensitive Prostate Cancer

Kouji Izumi, Hiroaki Iwamoto, Takahiro Nohara, Shohei Kawaguchi et al.
5 citations
Cancers
Prostate Cancer Treatment and Research
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article

Novel Treatment Strategies for Low-Risk Metastatic Castration-Sensitive Prostate Cancer

Kouji Izumi, Hiroaki Iwamoto, Takahiro Nohara, Shohei Kawaguchi, Renato Naito, Atsushi Mizokami, Hiroshi Yaegashi, Tomohiro Hori, Kazuyoshi Shigehara, Ryunosuke Nakagawa, Tomoyuki Makino, Hiroshi Kano
article en
5 citations

Abstract

The Canazawa classification differentiated the prognosis of mCSPC patients more clearly. A PSA reduction rate of <95% at 12 w after starting ADT in low-risk, low-volume patients of all risk classifications was significantly shorter than the TTCR. We propose a new treatment strategy, in which patients with low-risk mCSPC are treated with ADT and switched to ARSIs based on the rate of PSA reduction at 12 w.

CancersVol. 16(18)
Kanazawa University (JP)
Openalex Percentile: Top 12%
Prostate Cancer Treatment and Research
2.09
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