Low-Density Lipoprotein Cholesterol Gymnastics: Exploring the Advantages and Limitations of the Friedewald, Martin–Hopkins, and Sampson Equations for Personalized Lipid Management
The Martin-Hopkins equation is a superior method for LDL-C estimation and a valuable tool in precision medicine. However, clinicians and laboratory professionals must be aware of its limitations and recognize patterns that could lead to significant LDL-C underestimation. We propose an algorithm for clinical laboratories to provide personalized LDL-C assessments.
Authors
- Minodora Dobreanu (ORCID: https://orcid.org/0000-0003-3214-3631)
- Ion Bogdan Mănescu (ORCID: https://orcid.org/0000-0001-6797-8757)
- Liliana Demian
Institutions
- Universitatea de Medicină, Farmacie, Științe și Tehnologie „George Emil Palade” din Târgu Mureș (RO)
- Spitalul Clinic Judetean de Urgenta Târgu Mureş (RO)
Publication Details
- Journal
- Journal of Personalized Medicine
- Published
- 2024-09-20
- DOI
- https://doi.org/10.3390/jpm14091000
- Citations
- 3
- Primary Topic
- Lipoproteins and Cardiovascular Health
- Type
- article
- Field-Weighted Citation Impact
- 1.72
Funders
- National Authority for Scientific Research and Innovation
- Autoritatea Natională pentru Cercetare Stiintifică
- Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii