Treatment of recurrent aphthous stomatitis with oral roflumilast, a multicenter observational study

This study suggests that roflumilast may effectively treat RAS by reducing the number of flare-ups and ulcers, their duration, and the symptomatology produced by the ulcers. In addition, roflumilast has a good safety profile, is well tolerated at low doses, and does not require close monitoring. These characteristics and its favorable economic profile make roflumilast a promising therapeutic option in this pathology.

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Publication Details

Journal
International Journal of Dermatology
Published
2024-09-20
DOI
https://doi.org/10.1111/ijd.17478
Citations
5
Primary Topic
Medicinal plant effects and applications
Type
article
Field-Weighted Citation Impact
3.58
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article

Treatment of recurrent aphthous stomatitis with oral roflumilast, a multicenter observational study

Carolina Labrandero Hoyos, Leticia Bagán, Ángel González García, Rodrigo Peñuelas Leal et al.
5 citations
International Journal of Dermatology
Medicinal plant effects and applications
3.58
article

Treatment of recurrent aphthous stomatitis with oral roflumilast, a multicenter observational study

Carolina Labrandero Hoyos, Leticia Bagán, Ángel González García, Rodrigo Peñuelas Leal, José Vicente Bagán Sebastián, Malena Finello, Andrés Grau Echevarría, Sandra Martínez‐Fernández, Daniel Blaya Imbernón, Elena Pérez Zafrilla, Violeta Zaragozá Ninet, Jose Amancio Peñuelas Ruiz, Gemma Pérez Pastor, José Luís Sánchez Carazo, Miguel Martí Cabrera
article en
5 citations

Abstract

This study suggests that roflumilast may effectively treat RAS by reducing the number of flare-ups and ulcers, their duration, and the symptomatology produced by the ulcers. In addition, roflumilast has a good safety profile, is well tolerated at low doses, and does not require close monitoring. These characteristics and its favorable economic profile make roflumilast a promising therapeutic option in this pathology.

International Journal of DermatologyVol. 63(12)
Universitat de València (ES), Hospital General Universitario De Valencia (ES), Complejo Hospitalario de Pontevedra (ES)
Openalex Percentile: Top 8%
Medicinal plant effects and applications
3.58
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