Effect Of 7-days Supplementation Of Piceatannol On Fat Oxidation At Rest, During And After Exercise

Takuma Morishima1, Kanon Hayashi2, Masaki Kitoh1 and Nobukazu Kasai21Chukyo University, Aichi, Japan2Aichi Shukutoku University, Aichi, Japan ABSTRACT: Piceatannol is a type of polyphenol, and can be abundantly obtained from passion fruit. Several reports have shown that piceatannol supplementation has various effects, such as a vasorelaxant effect by upregulation of endothelial nitric oxide synthase expression; however, the effect of piceatannol supplementation on fat metabolism at rest, during and after exercise is unknown. PURPOSE: The purpose of the present study was to determine the effect of 7 days of piceatannol supplementation on fat oxidation at rest, during and after low-intensity aerobic exercise. METHODS: Eight physical active male subjects participated in the present study. This study was conducted using a randomized, a double-blind and crossover design. Participants completed two experimental trials: 1) placebo trial; 2) piceatannol trial. The participants ingested either a placebo or piceatannol tablets that contain 0 or 10 mg of piceatannol for seven consecutive days. After each seven days, participants arrived at the laboratory. Following baseline measurements, participants performed 60 min of pedaling exercise at 30% of their maximum oxygen uptake. Before, during, and after the exercise, respiratory gas and blood samples were collected. RESULTS: There were no significant differences between trials in oxygen uptake, carbon dioxide output, ventilation, and respiratory exchange ratio either at rest (0.79 ± 0.04 in the placebo trial vs. 0.81 ± 0.09 in the piceatannol trial, P > 0.05), during (just before the end of exercise: 0.86 ± 0.01 in the placebo trial vs. 0.88 ± 0.02 in the piceatannol trial, P > 0.05) and after the exercise. Similarly, serum growth hormone, serum cortisol, serum insulin, serum acetoacetic acid, serum 3-hydroxybutyric acid, serum ketone bodies, and serum FFA (at rest: 488 ± 158 μEq/L in the placebo trial vs. 423 ± 185 μEq/L in the piceatannol trial, just before the end of exercise: 706 ± 162 μEq/L in the placebo trial vs. 629 ± 236 μEq/L in the piceatannol trial, P > 0.05) responses were not significant differences between trials. CONCLUSION: Seven days of piceatannol supplementation did not promote fat oxidation at rest, during and after the low-intensity aerobic exercise.