The Association Of VISA-A, UWRI, And PROMIS-29 Measures In Quantifying Function Of Runners With Non-insertional Achilles Tendinopathy

The Association of VISA-A, UWRI, and PROMIS-29 Measures in Quantifying Function of Runners with Non-insertional Achilles tendinopathy INTRODUCTION: Achilles tendinopathy (AT) is a common running-related injury (RRI) that negatively impacts health. Symptom severity can be measured by the Victorian Institute of Sport Assessment (VISA-A), while the University of Wisconsin Running Injury and Recovery Index (UWRI) evaluates impact of RRI. PROMIS-29 assesses pain intensity and seven health domains. The associations between VISA-A, UWRI, and essential health domains in PROMIS-29 remain unexplored. PURPOSE: To evaluate association of VISA-A, UWRI, and PROMIS-29 scores in runners with AT. We hypothesize lower VISA-A and UWRI scores correlate with reduced physical function and other PROMIS-29 measures. METHODS: Forty-five runners diagnosed with >3 months of non-insertional AT (41 ± 12 years-old, BMI 23.4 ± 2.5 kg/m2; 21 female and 24 male) enrolled in an intervention study. Inclusion criteria included a VISA-A baseline score less than 80 and symptom duration >3 months. Baseline assessments included UWRI, PROMIS-29, and VISA-A. T-scores were calculated for each domain of the PROMIS-29. Spearman’s rank correlation coefficients were calculated for each outcome including VISA-A, UWRI, and PROMIS-29 subscales and pain intensity. RESULTS: Higher VISA-A scores correlated with improved physical function, higher UWRI scores, and reduced pain intensity and interference. A negative association was observed with runners’ scores on the UWRI and pain intensity (all p < 0.05) (Table 1). Table 1. - Correlation Coefficients of Patient Reported Outcome Measures (Spearman”s rho) Physical Function Anxiety Depression Fatigue Sleep Disturbance Social Roles and Activities Pain Interference Pain Intensity VISA-A UWRI Physical Function 1.000 0.207 0.004 0.112 0.252 0.079 -.497** -.365* .376* 0.240 Anxiety 0.207 1.000 .534** 0.287 0.110 -0.282 -0.008 -0.108 -0.154 -0.037 Depression 0.004 .534** 1.000 .415** 0.174 -0.281 -0.112 -0.261 -0.002 -0.008 Fatigue 0.112 0.287 .415** 1.000 .489** 0.025 -0.219 0.023 -0.061 -0.024 Sleep Disturbance 0.252 0.110 0.174 .489** 1.000 0.202 -0.105 -0.027 -0.180 -0.129 Social Roles and Activities 0.079 -0.282 -0.281 0.025 0.202 1.000 -0.195 0.186 0.108 -0.014 Pain Interference -.497** -0.008 -0.112 -0.219 -0.105 -0.195 1.000 .510** -.425** -0.277 Pain Intensity -.365* -0.108 -0.261 0.023 -0.027 0.186 .510** 1.000 -.555** -.356* VISA-A .376* -0.154 -0.002 -0.061 -0.180 0.108 -.425** -.555** 1.000 .670** UWRI 0.240 -0.037 -0.008 -0.024 -0.129 -0.014 -0.277 -.356* .670** 1.000 CONCLUSION: Our results reveal associations between VISA-A, UWRI, and PROMIS-29 in quantifying the influence of functional impairment from AT to other domains of health. Not all measures of health align with functional impairments, suggesting that multiple patient reported outcomes are required to capture both physical function along with sleep, fatigue, social roles, depression, and anxiety. Clinical study funded by Geneva Foundation.