Effectiveness Of Tele-exercise Training On Physical Fitness, Functional Capacity, And Health-related Quality Of Life In Non-hospitalized Patients With Covid-19: The Cofit-hk Study

The use of tele-exercise programs as a rehabilitation option for individuals with COVID-19 has been suggested, but its effectiveness in non-hospitalized patients is not well understood. PURPOSE: This study aimed to determine the effectiveness of an 8-week tele-exercise training program (COFIT-HK) on physical fitness, functional capacity, and health-related quality of life (HRQoL) in non-hospitalized COVID-19 patients. METHODS: Forty-one non-hospitalized individuals (age:47.4 ± 7.8 yrs) who had COVID-19 were divided into two groups: the tele-exercise training group (TELE; n = 21) and the non-intervention control group (CON; n = 20). TELE engaged in online supervised multicomponent low-to-moderate intensity exercise training (including respiratory muscle, aerobic, and resistance training) three times per week, whereas CON received standardized educational leaflets based on World Health Organization (WHO) guidelines for post-COVID-19-related illness rehabilitation only. Various components of physical fitness, functional capacity, and HRQoL were assessed at baseline and after the 8-week intervention. RESULTS: TELE showed significant improvements in handgrip strength, arm flexibility, functional lower extremity endurance, and HRQoL after the 8-week intervention (all p < 0.05, ES = 0.50-1.10). When comparing the groups, TELE demonstrated significantly greater improvements in both the physical and mental component summary scores of HRQoL compared to CON (both p < 0.05). Other outcomes did not reveal significant group differences. CONCLUSIONS: Our tele-exercise intervention was effective in improving physical fitness, functional capacity and HRQoL among non-hospitalized COVID-19 patients. Further research is needed to explore the utility and limitations of tele-exercise programs for post-COVID-19 rehabilitation and beyond. Knowledge Transfer Fund, The Education University of Hong Kong