Characterization of the angiomodulatory effects of Interleukin 11 cis- and trans-signaling in the retina
Cis- and trans-signaling by IL-11 have contrasting angiomodulatory effects on endothelial cells in vitro. In vivo, cis- and trans-signaling also influence Müller cells, ultimately determining the overall angiomodulatory impact on the retina, highlighting the intricate interplay between vascular and glial cells in the retina.
Authors
- Paula Liang
- Günther Schlunck (ORCID: https://orcid.org/0000-0002-0355-7766)
- Hansjürgen Agostini (ORCID: https://orcid.org/0000-0002-0331-1109)
- Stefaniya Boneva (ORCID: https://orcid.org/0000-0002-9811-2160)
- Melanie Schwämmle (ORCID: https://orcid.org/0000-0002-9040-3879)
- Felicitas Bucher (ORCID: https://orcid.org/0000-0003-0081-1420)
- Julian Rapp (ORCID: https://orcid.org/0000-0001-6770-8116)
- Jan Ness
- Malte Jung
Institutions
- University of Freiburg (DE)
- University Medical Center Freiburg (DE)
Publication Details
- Journal
- Journal of Neuroinflammation
- Published
- 2024-09-18
- DOI
- https://doi.org/10.1186/s12974-024-03223-3
- Citations
- 1
- Primary Topic
- interferon and immune responses
- Type
- article
- Field-Weighted Citation Impact
- 0.24