Immunogenicity and Neutralization Potential of Recombinant Chimeric Protein Comprising the Catalytic Region of Gp63 of Leishmania and LTB against Leishmania donovani
It could be concluded that the hybrid protein containing catalytic motif L. donovani gp63 protein and carrier protein (LTB) could elicit antibodies that could neutralise the functional activity of gp63 and thus could be a potential candidate for subunit leishmaniasis vaccine.
Authors
- Anuja Krishnan (ORCID: https://orcid.org/0000-0001-6538-2044)
- Lalit C. Garg (ORCID: https://orcid.org/0000-0001-6640-5383)
- Gunjan Malik (ORCID: https://orcid.org/0009-0003-6705-5858)
Institutions
- Jamia Hamdard (IN)
- National Institute of Immunology (IN)
Publication Details
- Journal
- Protein and Peptide Letters
- Published
- 2024-09-01
- DOI
- https://doi.org/10.2174/0109298665325330240828115712
- Citations
- 2
- Primary Topic
- Research on Leishmaniasis Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.09