Synthesis of New Chromen-5-one Derivatives from Dimedone and their Antiproliferative Evaluations against Selected Cancer Cell Lines Together with Hepatocellular Carcinoma and Cervical Carcinoma
The synthesized heterocyclic compounds were originally obtained from 5,5-dimethylcyclohexane- 1,3-dione. Several of the produced compounds exhibited high inhibitions toward several cancer cell lines proving high inhibitions, therefore, encouraging further studies to synthesize heterocyclic compounds based on chromene scaffold.
Authors
- Rasha Jame (ORCID: https://orcid.org/0000-0003-0262-2850)
- Rafat M. Mohareb
- Mahmoud Ali Abdelaziz (ORCID: https://orcid.org/0000-0002-1317-0653)
- Noha Omer (ORCID: https://orcid.org/0000-0001-9705-4205)
- Hanan Maged Labib
Institutions
- Cairo University (EG)
- University of Tabuk (SA)
Publication Details
- Journal
- Anti-Cancer Agents in Medicinal Chemistry
- Published
- 2024-09-20
- DOI
- https://doi.org/10.2174/0118715206323592240909101754
- Citations
- 1
- Primary Topic
- Synthesis of Organic Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.45