Type 2-like polarization and elevated CXCL4 secretion of monocyte derived macrophages upon internalization of plasma-derived exosomes from head and neck cancer patients
The study provides new insights regarding exosome driven pro-tumorigenic immune regulation in the circulation of patients with head and neck cancer and could help to better understand the individual immunologic situation.
Authors
- Jonas Fleckner
- Ralph Pries (ORCID: https://orcid.org/0000-0003-4056-0654)
- Kirstin Plötze‐Martin
- Cornelia Brunner (ORCID: https://orcid.org/0000-0002-6456-5508)
- Linda Hofmann (ORCID: https://orcid.org/0000-0002-0683-7659)
- Marie‐Nicole Theodoraki (ORCID: https://orcid.org/0000-0002-5491-1593)
- Diana Huber (ORCID: https://orcid.org/0009-0005-7931-4831)
- Reinhard Depping (ORCID: https://orcid.org/0000-0002-4860-6058)
- Thomas K. Hoffmann (ORCID: https://orcid.org/0000-0001-5127-3779)
- Lotte Werner
- Lutz Schütt
- Karl‐Ludwig Bruchhage
- Christian Idel
Institutions
- Universität Ulm (DE)
- Institute for Integrative and Experimental Genomics (DE)
- Technical University of Munich (DE)
- University of Lübeck (DE)
Publication Details
- Journal
- BMC Cancer
- Published
- 2024-09-20
- DOI
- https://doi.org/10.1186/s12885-024-12948-6
- Citations
- 8
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 1.87
Funders
- Universität zu Lübeck