Exploring free pregnancy associated plasma protein a (fPAPP-A) as a biomarker in early pregnancy

Investigating fPAPP-A presence and concentration directly in first trimester serum has not been done previously. This study report lower fPAPP-A values than anticipated from prior enzymatic studies of fPAPP-A. fPAPP-A was not superior to PAPP-A as a first trimester biomarker in this dataset.

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Publication Details

Journal
Practical Laboratory Medicine
Published
2024-09-16
DOI
https://doi.org/10.1016/j.plabm.2024.e00428
Primary Topic
Pregnancy and preeclampsia studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Exploring free pregnancy associated plasma protein a (fPAPP-A) as a biomarker in early pregnancy

Jesper Friis Petersen, Lennart Friis‐Hansen, Saara Wittfooth, Ellen Løkkegaard et al.
Practical Laboratory Medicine
Pregnancy and preeclampsia studies
article

Exploring free pregnancy associated plasma protein a (fPAPP-A) as a biomarker in early pregnancy

Jesper Friis Petersen, Lennart Friis‐Hansen, Saara Wittfooth, Ellen Løkkegaard, Vilma Tiittanen
article en

Abstract

Investigating fPAPP-A presence and concentration directly in first trimester serum has not been done previously. This study report lower fPAPP-A values than anticipated from prior enzymatic studies of fPAPP-A. fPAPP-A was not superior to PAPP-A as a first trimester biomarker in this dataset.

Practical Laboratory MedicineVol. 42
University of Copenhagen (DK), University of Turku (FI), Bispebjerg Hospital (DK), Zealand University Hospital (DK), Turku Centre for Biotechnology (FI)
Region Hovedstaden, Gangstedfonden, Fonden for Faglig Udvikling af Speciallægepraksis, Det Sundhedsvidenskabelige Fakultet, Københavns Universitet
Openalex Percentile: Top 75%
Pregnancy and preeclampsia studies
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