Evaluation of the attributable fraction and burden of HPV-related oropharyngeal cancers in Greece—the ORPHEAS study
In Greece, we observed a high HPV-AF (52.1%) in OPC, approximating the AFs reported for some Northern European countries. HPV+ versus HPV- patients were younger, more frequently with tonsillar tumors, and less frequently at TNM stage IV. Since most patients were infected by ≥1 HPV type targeted by the 9-valent vaccine, the HPV+ OPC burden could be mitigated through a routine HPV gender-neutral vaccination program.
Authors
- Panagiota Economopoulou
- Ioannis G. Panayiotides (ORCID: https://orcid.org/0000-0001-7339-8193)
- Ioannis Boukovinas (ORCID: https://orcid.org/0000-0003-4475-1802)
- L. Poughias
- Sofia Agelaki (ORCID: https://orcid.org/0000-0002-7850-0457)
- Eleni Litsou
- C Athanasopoulos
- Georgios Psychogios (ORCID: https://orcid.org/0000-0002-7805-3714)
- Aris Spathis (ORCID: https://orcid.org/0000-0001-8867-3661)
- Efthymios Kyrodimos (ORCID: https://orcid.org/0000-0001-5236-7961)
- Spyridon Lygeros (ORCID: https://orcid.org/0000-0003-0642-6697)
- Georgios Trimis
- Yannis Dimitriadis (ORCID: https://orcid.org/0000-0001-7275-2242)
- S Zioga
- K Ploiarchopoulou
- A. Psyrri
- J. Constantinidis
Institutions
- National and Kapodistrian University of Athens (GR)
- AHEPA University Hospital (GR)
- General University Hospital of Patras (GR)
- Athens Medical Center (GR)
- University Hospital of Heraklion (GR)
- University Hospital of Ioannina (GR)
- Metropolitan Hospital (GR)
Publication Details
- Journal
- ESMO Open
- Published
- 2024-09-19
- DOI
- https://doi.org/10.1016/j.esmoop.2024.103724
- Citations
- 1
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.58
Funders
- Ipsen