Intralesional gene expression profile of JAK-STAT signaling pathway and associated cytokines in Leishmania tropica-infected patients
Our finding revealed dysregulation of cytokines and related <i>jak-stat</i> genes in the lesion of CL patients. These results highlight the need for further exploration of the functional importance of these genes in the pathogenesis of, and immunity to, CL.
Authors
- Hosein Heydari (ORCID: https://orcid.org/0000-0002-8627-9625)
- Nasim Tootoonchi (ORCID: https://orcid.org/0000-0001-8548-2130)
- Maryam Daneshpazhooh (ORCID: https://orcid.org/0000-0003-1020-8895)
- Nasrin Masoudzadeh (ORCID: https://orcid.org/0000-0003-2198-7249)
- Shima Hadifar (ORCID: https://orcid.org/0000-0003-4702-634X)
- Ali M. Harandi
- Vahid Mashayekhi Goyonlo (ORCID: https://orcid.org/0000-0002-6615-3144)
- Sima Rafati (ORCID: https://orcid.org/0000-0002-7221-1320)
- Mohammadali Kerachian
- Ali Sadeghnia
- Reza Erfanian Salim
Institutions
- Pasteur Institute of Iran (IR)
- Mashhad University of Medical Sciences (IR)
- Noor Eye Hospital (IR)
- Razi Hospital (IR)
- Tehran University of Medical Sciences (IR)
- University of Gothenburg (SE)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2024-09-19
- DOI
- https://doi.org/10.3389/fimmu.2024.1436029
- Citations
- 5
- Primary Topic
- Research on Leishmaniasis Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- European Commission
- Pasteur Institute of Iran
- Horizon 2020 Framework Programme