Optimizing tacrolimus dosing in Hispanic renal transplant patients: insights from real-world data

Hispanic renal transplant population showed an estimated 40% decrease of apparent clearance in the typical patient compared to other populations with similar characteristics. The proposed dose adjustment attained the target range rapidly and safely. This study advocates for tailored tacrolimus dosing regimens based on population pharmacokinetics to optimize therapy in Hispanic renal transplant recipients.

Authors

Institutions

Publication Details

Journal
Frontiers in Pharmacology
Published
2024-09-19
DOI
https://doi.org/10.3389/fphar.2024.1443988
Citations
1
Primary Topic
Renal Transplantation Outcomes and Treatments
Type
article
Field-Weighted Citation Impact
0.51
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Optimizing tacrolimus dosing in Hispanic renal transplant patients: insights from real-world data

Mathangi Gopalakrishnan, Eglis Tellez, Jogarao Gobburu, Athanasios Chamzas et al.
1 citations
Frontiers in Pharmacology
Renal Transplantation Outcomes and Treatments
0.51
article

Optimizing tacrolimus dosing in Hispanic renal transplant patients: insights from real-world data

Mathangi Gopalakrishnan, Eglis Tellez, Jogarao Gobburu, Athanasios Chamzas, Andrew B. SyBing
article en
1 citations

Abstract

Hispanic renal transplant population showed an estimated 40% decrease of apparent clearance in the typical patient compared to other populations with similar characteristics. The proposed dose adjustment attained the target range rapidly and safely. This study advocates for tailored tacrolimus dosing regimens based on population pharmacokinetics to optimize therapy in Hispanic renal transplant recipients.

Frontiers in PharmacologyVol. 15
University of Maryland, Baltimore (US), St. Joseph Hospital (US)
Good health and well-being
Openalex Percentile: Top 35%
Renal Transplantation Outcomes and Treatments
0.51
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.