Optimizing tacrolimus dosing in Hispanic renal transplant patients: insights from real-world data
Hispanic renal transplant population showed an estimated 40% decrease of apparent clearance in the typical patient compared to other populations with similar characteristics. The proposed dose adjustment attained the target range rapidly and safely. This study advocates for tailored tacrolimus dosing regimens based on population pharmacokinetics to optimize therapy in Hispanic renal transplant recipients.
Authors
- Mathangi Gopalakrishnan (ORCID: https://orcid.org/0000-0003-2881-9870)
- Eglis Tellez
- Jogarao Gobburu (ORCID: https://orcid.org/0000-0002-8348-4295)
- Athanasios Chamzas
- Andrew B. SyBing
Institutions
- University of Maryland, Baltimore (US)
- St. Joseph Hospital (US)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-09-19
- DOI
- https://doi.org/10.3389/fphar.2024.1443988
- Citations
- 1
- Primary Topic
- Renal Transplantation Outcomes and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.51