AMP‐activated protein kinase in the amygdala and hippocampus contributes to enhanced fear memory in diabetic mice
In diabetic mice, L-lactate is increased in the amygdala and hippocampus, possibly through hyperglycaemia, which strengthens fear memory through inhibition of AMPK and activation of glutamatergic function.
Authors
- Seiji Shioda (ORCID: https://orcid.org/0000-0002-4164-6743)
- Hiroko Ikeda (ORCID: https://orcid.org/0000-0002-7278-7282)
- John L. Waddington (ORCID: https://orcid.org/0000-0003-3755-3373)
- Naomi Yonemochi (ORCID: https://orcid.org/0000-0003-3409-4212)
- Ai Kimura (ORCID: https://orcid.org/0000-0001-5641-514X)
- Aimi Yamagishi
- Fumiko Takenoya (ORCID: https://orcid.org/0000-0001-7029-1825)
Institutions
- Hoshi University (JP)
Publication Details
- Journal
- British Journal of Pharmacology
- Published
- 2024-09-18
- DOI
- https://doi.org/10.1111/bph.17338
- Citations
- 1
- Primary Topic
- Pancreatic function and diabetes
- Type
- article
- Field-Weighted Citation Impact
- 0.57
Funders
- Ministry of Education, India
- Hoshi University