Facile Synthesis of Diverse 1,3,5‐Trisubstituted 1,2,4‐Triazole using Hydrazones with Aldehydes, Alkenes, Amines
Abstract An efficient, and easy method for the synthesis of 1,3,5‐ substituted 1,2,4‐triazole derivatives by [3+2] annulation reactions of hydrazones with aldehydes, alkenes, or amines has been established. This strategy is characterized by the use of inexpensive and readily available oxidants and starting materials, a broader substrate scope, and moderate to good yields.
Authors
- Shuaikun Liu
- Lizhen Fang (ORCID: https://orcid.org/0000-0001-8594-4710)
- Xinqiang Tan (ORCID: https://orcid.org/0000-0003-2200-9340)
- Yi Liu (ORCID: https://orcid.org/0000-0002-3954-6102)
- Jialiang Zhang (ORCID: https://orcid.org/0000-0002-7421-8024)
- Kunyi Zhang (ORCID: https://orcid.org/0009-0007-8769-6870)
- Yu Song (ORCID: https://orcid.org/0000-0002-3803-8464)
Institutions
- Henan Medical University (CN)
Publication Details
- Journal
- Asian Journal of Organic Chemistry
- Published
- 2024-09-19
- DOI
- https://doi.org/10.1002/ajoc.202400424
- Citations
- 1
- Primary Topic
- Synthesis and Characterization of Heterocyclic Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.25