Mineralocorticoid receptor antagonist monotherapy in pediatric non-classical 11β-hydroxylase deficiency

CAH caused by 11βOHD is a known cause of hypertension. It is usually managed with glucocorticoids, and antihypertensives are added if blood pressure remains uncontrolled. In this case, glucocorticoid therapy was not tolerated and treatment with aldosterone antagonist monotherapy was effective in controlling his hypertension.

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Publication Details

Journal
Journal of Pediatric Endocrinology and Metabolism
Published
2024-09-19
DOI
https://doi.org/10.1515/jpem-2024-0194
Primary Topic
Sexual Differentiation and Disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Mineralocorticoid receptor antagonist monotherapy in pediatric non-classical 11β-hydroxylase deficiency

Elaine Kennedy, Colin P. Hawkes, Maeve Durkan, Caroline Joyce et al.
Journal of Pediatric Endocrinology and Metabolism
Sexual Differentiation and Disorders
article

Mineralocorticoid receptor antagonist monotherapy in pediatric non-classical 11β-hydroxylase deficiency

Elaine Kennedy, Colin P. Hawkes, Maeve Durkan, Caroline Joyce, Eirin Carolan, Maria Stack
article en

Abstract

CAH caused by 11βOHD is a known cause of hypertension. It is usually managed with glucocorticoids, and antihypertensives are added if blood pressure remains uncontrolled. In this case, glucocorticoid therapy was not tolerated and treatment with aldosterone antagonist monotherapy was effective in controlling his hypertension.

Journal of Pediatric Endocrinology and MetabolismVol. 37(12)
University College Cork (IE), Bon Secours Hospital Cork (IE), Cork University Hospital (IE), Children's Health Ireland at Crumlin (IE), Infant (IE), University of Pennsylvania (US)
Good health and well-being
Openalex Percentile: Top 86%
Sexual Differentiation and Disorders
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Mineralocorticoid receptor antagonist monotherapy in pediatric non-classical 11β-hydroxylase deficiency — Elaine Kennedy, Colin P. Hawkes, et al. · Journal of Pediatric Endocrinology and Metabolism (2024) | TGRS Research Map | TGRS