Access to (<i>E</i>)-<i>N</i>′-benzylidene-<i>N</i>-(2-(phenylsulfonyl)ethyl)acetohydrazide via C(sp<sup>2</sup>)−H activation and reduction of (<i>E</i>)-<i>N</i>′-benzylideneacetohydrazide with (vinylsulfonyl)benzene
A novel route for C(sp 3 )-N bond formation via C(sp 2 )−H activation/reduction by metal-free which uses ( E)- N′-benzylideneacetohydrazide and (vinylsulfonyl)benzene to synthesize derivatives of ( E)- N′-benzylidene- N-(2-(phenylsulfonyl)ethyl)acetohydrazide has been reported. This methodology features good functional group tolerance and convenient operation. In addition, it uses inexpensive and insensitive chemical reagents as raw materials and provides an atom- and efficient method for the preparation of ( E)- N′-benzylidene- N-(2-(phenylsulfonyl)ethyl)acetohydrazides.
Authors
- H F Wang (ORCID: https://orcid.org/0009-0007-5973-9044)
- Fusheng Liu (ORCID: https://orcid.org/0000-0002-4909-1252)
Institutions
- Qingdao University of Science and Technology (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Journal of Chemical Research
- Published
- 2024-09-01
- DOI
- https://doi.org/10.1177/17475198241275297
- Primary Topic
- Synthesis and Catalytic Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Shandong First Medical University