Intraperitoneally Administered Vancomycin Results in Suboptimal Serum and Peritoneal Effluent Drug Levels in Patients with PD-related Peritonitis

In patients with PD-related peritonitis, intermittent intraperitoneal administration of 15 mg/kg of vancomycin every 96 h does not achieve the recommended serum and dialysate levels of vancomycin. There is an urgent need for pharmacokinetic studies on commonly used IP antibiotics in the PD population to facilitate correct dose recommendations.

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Publication Details

Journal
Indian Journal of Nephrology
Published
2024-09-19
DOI
https://doi.org/10.25259/ijn_59_2024
Primary Topic
Dialysis and Renal Disease Management
Type
article
Field-Weighted Citation Impact
0.00

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article

Intraperitoneally Administered Vancomycin Results in Suboptimal Serum and Peritoneal Effluent Drug Levels in Patients with PD-related Peritonitis

Sandhiya Selvarajan, PS Priyamvada, Kapil Navin Sejpal, Sreejith Parameswaran et al.
Indian Journal of Nephrology
Dialysis and Renal Disease Management
article

Intraperitoneally Administered Vancomycin Results in Suboptimal Serum and Peritoneal Effluent Drug Levels in Patients with PD-related Peritonitis

Sandhiya Selvarajan, PS Priyamvada, Kapil Navin Sejpal, Sreejith Parameswaran, Ezhilnilavan Sampath, Apurba Sastry
article en

Abstract

In patients with PD-related peritonitis, intermittent intraperitoneal administration of 15 mg/kg of vancomycin every 96 h does not achieve the recommended serum and dialysate levels of vancomycin. There is an urgent need for pharmacokinetic studies on commonly used IP antibiotics in the PD population to facilitate correct dose recommendations.

Indian Journal of NephrologyVol. 35(4)
Jawaharlal Institute of Post Graduate Medical Education and Research (IN)
Jawaharlal Institute Of Postgraduate Medical Education and Research
Openalex Percentile: Top 80%
Dialysis and Renal Disease Management
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