Efficacy and safety of SKCPT in patients with knee osteoarthritis: A multicenter, randomized, double-blinded, active-controlled phase III clinical trial
SKCPT efficacy was non-inferior, and its safety profile was similar, to celecoxib. Building on previous results showing that SYSADOA reduce NSAID intake, the present results suggest that the SYSADOA SKCPT could effectively replace NSAIDs in knee OA treatment while avoiding long-term side effects.
Authors
- Jong Keun Seon (ORCID: https://orcid.org/0000-0002-6450-2339)
- Jae Ang Sim (ORCID: https://orcid.org/0000-0002-2055-6458)
- Yong In (ORCID: https://orcid.org/0000-0002-5932-3934)
- Kyoung Ho Yoon (ORCID: https://orcid.org/0000-0001-8913-7932)
- Seung‐Baik Kang (ORCID: https://orcid.org/0000-0002-1184-4482)
- Young‐Wan Moon (ORCID: https://orcid.org/0000-0001-6350-5530)
- Seung-Beom Han (ORCID: https://orcid.org/0000-0003-1880-4229)
- Chong Bum Chang (ORCID: https://orcid.org/0000-0002-8597-1054)
- Ki‐Cheor Bae (ORCID: https://orcid.org/0000-0002-4363-0956)
- Sung Il Bin
- Kwan Kyu Park (ORCID: https://orcid.org/0000-0003-0514-3257)
- Young Mo Kim (ORCID: https://orcid.org/0000-0002-6969-4499)
- Sang Jin Lee (ORCID: https://orcid.org/0000-0002-8871-8468)
- Myung Chul Lee
Institutions
- Chungnam National University (KR)
- Severance Hospital (KR)
- Seoul Metropolitan Government (KR)
- Asan Medical Center (KR)
- Samsung Medical Center (KR)
- Seoul National University Hospital (KR)
- Seoul National University Bundang Hospital (KR)
- Kyung Hee University (KR)
- Gachon University Gil Medical Center (KR)
- Inje University Haeundae Paik Hospital (KR)
- Kyung Hee University Medical Center (KR)
- Keimyung University Dongsan Medical Center (KR)
- Chungnam National University Hospital (KR)
- Chonnam National University Hwasun Hospital (KR)
- St. Paul's Hospital (KR)
- The Catholic University of Korea Seoul St. Mary's Hospital (KR)
- Korea University (JP)
- Keimyung University (KR)
- Naver (South Korea) (KR)
Publication Details
- Journal
- Journal of Ethnopharmacology
- Published
- 2024-09-19
- DOI
- https://doi.org/10.1016/j.jep.2024.118843
- Citations
- 8
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 3.76