Chronic stress induces insulin resistance and enhances cognitive impairment in AD
Chronic stress significantly affects hippocampal cognitive function through insulin resistance and exacerbates AD pathology. This study reveals the complex relationship between chronic stress, insulin resistance, and AD, providing new insights for developing interventions targeting chronic stress and insulin resistance.
Authors
- Yanyong Wang (ORCID: https://orcid.org/0000-0001-5007-5930)
- Bing Han (ORCID: https://orcid.org/0000-0001-8170-498X)
- Shen Li (ORCID: https://orcid.org/0000-0002-3022-1141)
- Mingwei Wang (ORCID: https://orcid.org/0000-0002-5729-2222)
- Jiaying Rong
- Qinying Ma
- Na Liu (ORCID: https://orcid.org/0000-0003-0949-4046)
Institutions
- Hebei Medical University (CN)
- Second Hospital of Hebei Medical University (CN)
- First Affiliated Hospital of Hebei Medical University (CN)
Publication Details
- Journal
- Brain Research Bulletin
- Published
- 2024-09-19
- DOI
- https://doi.org/10.1016/j.brainresbull.2024.111083
- Citations
- 13
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 2.05
Funders
- Natural Science Foundation of Hebei Province
- Hebei Province Medical Science Research Key Project