Intestinal gluconeogenesis controls the neonatal development of hypothalamic feeding circuits
These findings reveal that IGN at birth but not later during postnatal life controls the development of hypothalamic feeding circuits and sympathetic innervation of adipose tissues, promoting a better management of metabolism in adulthood.
Authors
- Adeline Duchampt
- Jasmine Videlo
- Marine Silva
- Gilles Mithieux (ORCID: https://orcid.org/0000-0003-3579-8529)
- Fabienne Rajas (ORCID: https://orcid.org/0000-0002-9233-7633)
- Clara Bron
- C. Saint-Béat
- Sébastien G. Bouret (ORCID: https://orcid.org/0000-0002-4174-9769)
- Judith Estrada-Meza (ORCID: https://orcid.org/0000-0002-9919-580X)
- Amandine Gautier‐Stein (ORCID: https://orcid.org/0000-0002-6003-1891)
- Mickael Zergane
Institutions
- Université Claude Bernard Lyon 1 (FR)
- Inserm (FR)
- Lyon College (US)
- Université de Lille (FR)
- Centre Hospitalier Universitaire de Lille (FR)
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR)
- Département Alimentation Humaine (FR)
- Centre de Recherche Jean Pierre Aubert (FR)
- Nutrition, Diabète et Cerveau
Publication Details
- Journal
- Molecular Metabolism
- Published
- 2024-09-19
- DOI
- https://doi.org/10.1016/j.molmet.2024.102036
- Primary Topic
- Regulation of Appetite and Obesity
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Commission
- Agence Nationale de la Recherche
- Institut National de la Santé et de la Recherche Médicale
- Centre National de la Recherche Scientifique
- Université Claude Bernard Lyon 1
- Société Francophone du Diabète