Target-Enhanced Whole-Genome Sequencing Shows Clinical Validity Equivalent to Commercially Available Targeted Oncology Panel
TE-WGS is a comprehensive approach in personalized oncology, matching TSO500's key biomarker detection capabilities. It uniquely identifies germline variants and genomic instability markers, offering additional clinical actions. Its adaptability and cost-effectiveness underscore its clinical utility, making TE-WGS a valuable tool in personalized cancer treatment.
Authors
- Jong-Yeon Shin (ORCID: https://orcid.org/0000-0001-5774-6477)
- Jin Roh (ORCID: https://orcid.org/0000-0002-3995-355X)
- Jaemo Koo
- Minsuk Kwon (ORCID: https://orcid.org/0000-0003-1833-6576)
- Seokhwi Kim (ORCID: https://orcid.org/0000-0001-7646-5064)
- Joonoh Lim (ORCID: https://orcid.org/0000-0002-2836-8259)
- Jung‐Ah Kim (ORCID: https://orcid.org/0000-0001-6934-1987)
- Mi Sun Ahn (ORCID: https://orcid.org/0000-0002-7081-9826)
- Seongyeol Park (ORCID: https://orcid.org/0000-0002-9236-5853)
- Young Seok Ju (ORCID: https://orcid.org/0000-0002-5514-4189)
- İslam Oğuz Tuncay (ORCID: https://orcid.org/0000-0002-3530-5854)
- Ryul Kim (ORCID: https://orcid.org/0000-0002-8754-9180)
- Jeong Seok Lee (ORCID: https://orcid.org/0000-0001-8261-7044)
- Erin Connolly-Strong
- Tae‐Hwan Kim (ORCID: https://orcid.org/0000-0002-3542-2276)
- Hyun Woo Lee (ORCID: https://orcid.org/0000-0002-6879-9686)
- Jun Sung Park (ORCID: https://orcid.org/0000-0001-7149-6769)
- Won‐Chul Lee (ORCID: https://orcid.org/0000-0001-8052-2420)
- Sangmoon Lee (ORCID: https://orcid.org/0000-0002-7723-5946)
- Jang‐Hee Kim (ORCID: https://orcid.org/0000-0001-5825-1361)
- Hansol Park (ORCID: https://orcid.org/0000-0002-2851-4404)
- Yong Won Choi
- Brian Baek-Lok Oh
Institutions
- Samsung Medical Center (KR)
- Ajou University (KR)
- Sungkyunkwan University (KR)
Publication Details
- Journal
- Cancer Research and Treatment
- Published
- 2024-09-19
- DOI
- https://doi.org/10.4143/crt.2024.114
- Citations
- 3
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.86
Funders
- National Research Foundation
- Korea Health Industry Development Institute
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea