Potential mechanistic linkages of Naoluotong granules on the remission of atherosclerosis by multidimensional analysis
Employing multidimensional analysis, we identified core pairs, components, and targets of NLTGs. Our multilevel analysis of DECCGs enabled the construction of a clinical prediction model, highlighting CTSB as a risk target for AS. Additionally, we unveiled NLTGs' mechanisms closely tied to the polarization and regulation of macrophage, facilitating subsequent research and application.
Authors
- Wandi Chen
- Wenyu Bu
- Yanzi Liu
- Fuming Liu (ORCID: https://orcid.org/0000-0002-5699-2008)
- Yanlin Liu
- Shidian Zhu
Institutions
- Nanjing University of Chinese Medicine (CN)
- Jiangsu Province Hospital (CN)
Publication Details
- Journal
- Heliyon
- Published
- 2024-09-19
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e37957
- Citations
- 1
- Primary Topic
- Neurological Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.25