18F-FDG brain PET: a metabolic predictive factor for gait improvement after cerebrospinal fluid shunting in normal pressure hydrocephalus?
This preliminary study using brain <sup>18</sup>F-FDG PET suggests that reduced brain metabolism in the thalamus and striatum along with cortical hypometabolism may be associated with poorer gait response to CSF shunting in normal pressure hydrocephalus (NPH). Although these findings suggest that preoperative brain 18F-FDG PET could potentially aid in selecting appropriate candidates for shunt surgery, further research with larger sample sizes is needed to confirm these results.
Authors
- Stéphan Grimaldi (ORCID: https://orcid.org/0000-0003-0849-8213)
- Thomas Graillon (ORCID: https://orcid.org/0000-0001-5627-8181)
- Tatiana Horowitz (ORCID: https://orcid.org/0000-0003-1977-309X)
- Éric Guedj (ORCID: https://orcid.org/0000-0003-1912-6132)
- Jean‐Philippe Azulay (ORCID: https://orcid.org/0000-0001-6624-3329)
- H. Dufour
Institutions
- Centre National de la Recherche Scientifique (FR)
- Centre de Résonance Magnétique Biologique et Médicale (FR)
Publication Details
- Journal
- The Quarterly Journal of Nuclear Medicine and Molecular Imaging
- Published
- 2024-09-01
- DOI
- https://doi.org/10.23736/s1824-4785.24.03582-9
- Citations
- 2
- Primary Topic
- Cerebrospinal fluid and hydrocephalus
- Type
- article
- Field-Weighted Citation Impact
- 0.54