Senolytic effect of triterpenoid complex from Ganoderma lucidum on adriamycin-induced senescent human hepatocellular carcinoma cells model in vitro and in vivo
A triterpenoid complex isolated from <i>G. lucidum</i> may serve as a novel senolytic agent against SCs, and its combination with chemotherapeutic agents may enhance their antitumor efficacy.
Authors
- Ahmed Attia Ahmed Abdelmoaty
- Changhui Wu (ORCID: https://orcid.org/0000-0002-3325-562X)
- Ye Li (ORCID: https://orcid.org/0000-0002-8875-9593)
- Kun Zhang (ORCID: https://orcid.org/0000-0002-6971-1164)
- Jianhua Xu (ORCID: https://orcid.org/0000-0002-8990-6604)
- Peng Li (ORCID: https://orcid.org/0000-0003-3741-6387)
- Jing Chen (ORCID: https://orcid.org/0000-0003-1099-3766)
Institutions
- Fujian Medical University (CN)
- Fujian Electric Power Survey & Design Institute (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-09-19
- DOI
- https://doi.org/10.3389/fphar.2024.1422363
- Citations
- 8
- Primary Topic
- Fungal Biology and Applications
- Type
- article
- Field-Weighted Citation Impact
- 3.58
Funders
- Ministry of Science and Technology