Isoliensinine suppressed gastric cancer cell proliferation and migration by targeting TGFBR1 to regulate TGF-β-smad signaling pathways
Our research suggests that ISO specifically targets TGFBR1 and regulates the TGF-β-Smad signaling pathway to suppress the proliferation and migration of GC cells.
Authors
- Shang‐Ming Dai
- Lichen Gao (ORCID: https://orcid.org/0000-0002-6182-691X)
- Shuo‐Guo Xu (ORCID: https://orcid.org/0009-0002-1970-4908)
- Jinda Hu
- Mengqin Yuan (ORCID: https://orcid.org/0000-0002-3957-0727)
- Fengjiao Li (ORCID: https://orcid.org/0000-0002-6153-7747)
Institutions
- Changsha Central Hospital (CN)
- University of South China (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2024-09-19
- DOI
- https://doi.org/10.3389/fphar.2024.1438161
- Citations
- 4
- Primary Topic
- Chromatography in Natural Products
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hunan Province
- University of South China