Unusual Verrucous Skin Lesion in Diabetic Neuropathy Following Toe Amputation and Skin Grafting

Verrucous skin lesions in diabetic neuropathy (VSLDN) are rare and typically occur at weight-bearing sites due to chronic mechanical stress. This case report describes a 35-year-old man with type 2 diabetes mellitus who developed a verrucous lesion on the dorsum of his left foot following toe amputation and skin grafting. Histological analysis identified pseudoepitheliomatous hyperplasia with no evidence of malignancy or human papillomavirus infection. The lesion gradually resolved with the application of maxacalcitol ointment and the use of elastic stockings. This case highlights the importance of recognizing atypical verrucous lesions in patients with diabetes, particularly at non-weight-bearing sites after surgical interventions. Accurate differentiation between plantar warts and verrucous carcinomas is essential for appropriate management. Effective treatment and comprehensive patient education on foot care are crucial for improving outcomes and preventing further complications in patients with diabetes.

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Publication Details

Journal
Cureus
Published
2024-09-19
DOI
https://doi.org/10.7759/cureus.69695
Primary Topic
Diabetic Foot Ulcer Assessment and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Unusual Verrucous Skin Lesion in Diabetic Neuropathy Following Toe Amputation and Skin Grafting

Takahiro Kobayashi, Akemi Ishida‐Yamamoto, Shin Iinuma, Akiko Watanabe
Cureus
Diabetic Foot Ulcer Assessment and Management
article

Unusual Verrucous Skin Lesion in Diabetic Neuropathy Following Toe Amputation and Skin Grafting

Takahiro Kobayashi, Akemi Ishida‐Yamamoto, Shin Iinuma, Akiko Watanabe
article en

Abstract

Verrucous skin lesions in diabetic neuropathy (VSLDN) are rare and typically occur at weight-bearing sites due to chronic mechanical stress. This case report describes a 35-year-old man with type 2 diabetes mellitus who developed a verrucous lesion on the dorsum of his left foot following toe amputation and skin grafting. Histological analysis identified pseudoepitheliomatous hyperplasia with no evidence of malignancy or human papillomavirus infection. The lesion gradually resolved with the application of maxacalcitol ointment and the use of elastic stockings. This case highlights the importance of recognizing atypical verrucous lesions in patients with diabetes, particularly at non-weight-bearing sites after surgical interventions. Accurate differentiation between plantar warts and verrucous carcinomas is essential for appropriate management. Effective treatment and comprehensive patient education on foot care are crucial for improving outcomes and preventing further complications in patients with diabetes.

CureusVol. 16(9)
Asahikawa Medical University (JP), Japanese Red Cross Hokkaido College of Nursing (JP)
Openalex Percentile: Top 76%
Diabetic Foot Ulcer Assessment and Management
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