Ailanthone suppresses cell proliferation of renal cell carcinoma partially via inhibition of EZH2
Altogether, we identified the anticancer role of Ail in RCC, including inhibition of cell proliferation and induction of apoptosis. The results also screened the key proteins mediate the function of Ail, which have laid a theoretical foundation for elucidating the applications of Ail in clinical research.
Authors
- Jianbing Zhu (ORCID: https://orcid.org/0000-0001-8186-9549)
- Lü Jin (ORCID: https://orcid.org/0000-0001-6408-3659)
- Jin Zhu (ORCID: https://orcid.org/0000-0003-0235-5465)
- Guangcheng Dai (ORCID: https://orcid.org/0000-0001-5037-4076)
- Ting Chen (ORCID: https://orcid.org/0000-0003-0179-3586)
- Lijun Xu (ORCID: https://orcid.org/0000-0002-5411-798X)
- Yachen Zang
- Yibin Zhou (ORCID: https://orcid.org/0009-0001-4187-0374)
Institutions
- Soochow University (CN)
- Second Affiliated Hospital of Soochow University (CN)
- Second Affiliated Hospital of Nanjing Medical University (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2024-09-19
- DOI
- https://doi.org/10.1007/s12672-024-01347-9
- Citations
- 1
- Primary Topic
- Cancer Mechanisms and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 0.42