Okanin Inhibits Cell Growth and Induces Apoptosis and Pyroptosis in Oral Cancer
Okanin demonstrates significant anticancer potential, particularly in oral cancer, by inducing both apoptosis and pyroptosis. Its efficacy in reducing tumor growth in vivo further supports its potential as a novel therapeutic option. Further mechanistic studies are needed to elucidate the pathways involved in okanin-mediated cell death and to explore its clinical applications.
Authors
- Sien-Lin Ho
- Wei‐Tso Chia (ORCID: https://orcid.org/0000-0002-9357-2360)
- Szu-Chien Chang
- Cheng‐Yu Yang (ORCID: https://orcid.org/0000-0002-5196-4032)
- Yi‐Ling Chen (ORCID: https://orcid.org/0000-0003-3758-0638)
- Bo Peng (ORCID: https://orcid.org/0000-0003-4158-3487)
- Cheng‐Chih Hsieh
- Kuei-Yuan Chen
- Yuan-Wu Chen
- Chih‐Kung Lin
- Chang-Huei Tsao
Institutions
- Tri-Service General Hospital (TW)
- Yuanpei University (TW)
- Taipei Tzu Chi Hospital (TW)
- Kaohsiung Armed Forces General Hospital (TW)
- National Taiwan University Hospital (TW)
- Kaohsiung Veterans General Hospital (TW)
- National Defense Medical Center (TW)
Publication Details
- Journal
- Cancers
- Published
- 2024-09-19
- DOI
- https://doi.org/10.3390/cancers16183195
- Citations
- 5
- Primary Topic
- Inflammatory mediators and NSAID effects
- Type
- article
- Field-Weighted Citation Impact
- 2.24