SFRP1 mediates cancer-associated fibroblasts to suppress cancer cell proliferation and migration in head and neck squamous cell carcinoma

SFRP1 inhibits the proliferation and migration of HNSCC cells by mediating CAFs, and the mechanism of action is related to the regulation of immune cells, which may provide new research directions and therapeutic targets for HNSCC.

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Publication Details

Journal
BMC Cancer
Published
2024-09-19
DOI
https://doi.org/10.1186/s12885-024-12907-1
Citations
6
Primary Topic
RNA modifications and cancer
Type
article
Field-Weighted Citation Impact
1.40

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article

SFRP1 mediates cancer-associated fibroblasts to suppress cancer cell proliferation and migration in head and neck squamous cell carcinoma

Xiaoyu Song, Caiyu Sun, Yumei Li, Xicheng Song et al.
6 citations
BMC Cancer
RNA modifications and cancer
1.40
article

SFRP1 mediates cancer-associated fibroblasts to suppress cancer cell proliferation and migration in head and neck squamous cell carcinoma

Xiaoyu Song, Caiyu Sun, Yumei Li, Xicheng Song, Lei Dong
article en
6 citations

Abstract

SFRP1 inhibits the proliferation and migration of HNSCC cells by mediating CAFs, and the mechanism of action is related to the regulation of immune cells, which may provide new research directions and therapeutic targets for HNSCC.

BMC CancerVol. 24(1)
Qingdao University (CN), Yuhuangding Hospital (CN)
China Postdoctoral Science Foundation, Natural Science Foundation of Shandong Province
Openalex Percentile: Top 19%
RNA modifications and cancer
1.40
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