Interaction of the gut microbiota and brain functional connectivity in late-life depression
We identified significant correlations between LDD-characterized gut microbes and brain FC, as well as depression severity, which may contribute to the pathophysiology of depression development among patients with LLD. Specific microbes were linked to altered brain connectivity, suggesting potential targets for treating LLD.
Authors
- Pei‐Chi Tu (ORCID: https://orcid.org/0000-0002-9403-4660)
- Chia-Hsien Chuang (ORCID: https://orcid.org/0000-0002-3639-4684)
- Yen‐Po Wang (ORCID: https://orcid.org/0000-0002-3769-0020)
- Chung‐Yen Lin (ORCID: https://orcid.org/0000-0002-4733-9488)
- Peiyi Liu (ORCID: https://orcid.org/0009-0005-6928-0877)
- Wan-Chen Chang (ORCID: https://orcid.org/0000-0003-2937-2687)
- Po-Shan Wu
- Chia-Fen Tsai
- Ching–Liang Lu
Institutions
- Taipei Veterans General Hospital (TW)
- Institute of Information Science, Academia Sinica (TW)
- Research Center for Applied Science, Academia Sinica (TW)
- Taipei Institute of Pathology (TW)
Publication Details
- Journal
- Journal of Psychiatry and Neuroscience
- Published
- 2024-09-19
- DOI
- https://doi.org/10.1503/jpn.240050
- Citations
- 7
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 2.29