Regioselective Cleavage and Reconfiguration of C–S Bonds with Diazo Compounds
A coupling reaction between diazo compounds and phenyl benzyl sulfide catalyzed by TfOH has been reported. This reaction can synthesize important α-arylthio carbonyl compounds via regioselective cleavage and reconfiguration of C-S bonds, and various functional groups were tolerant to the reaction conditions. Mechanistic studies have conclusively established that the pivotal intermediate in the reaction was meticulously investigated through spectroscopic evidence, complemented by rigorous control experiments.
Authors
- Fen‐Er Chen (ORCID: https://orcid.org/0000-0002-6734-3388)
- Haifeng Wang (ORCID: https://orcid.org/0000-0003-2277-4528)
- Shuang‐Xi Gu (ORCID: https://orcid.org/0000-0003-0159-4616)
- Huan Li (ORCID: https://orcid.org/0000-0003-4229-2796)
- Jie Zeng
- Zhimin Xia
- Lewan Li
- Jian Lv
Institutions
- Fudan University (CN)
- Wuhan Institute of Technology (CN)
Publication Details
- Journal
- Organic Letters
- Published
- 2024-09-19
- DOI
- https://doi.org/10.1021/acs.orglett.4c03246
- Citations
- 7
- Primary Topic
- Sulfur-Based Synthesis Techniques
- Type
- article
- Field-Weighted Citation Impact
- 1.75
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hubei Province
- Wuhan Institute of Technology