Exploring Genetic Variants and Platinum Chemotherapy Response in Indonesian Non-Small Cell Lung Cancer Patients: Insights from ERCC2 rs13181
This study did not find statistically significant associations between <i>ERCC2</i> rs13181 polymorphisms and chemotherapy responses. However, this research highlights the presence of genetic variation within the Indonesian population, with the AA genotype being the most prevalent, which may influence chemotherapy responses. The results provided preliminary data and lay the foundation for future comprehensive cohort observational investigations.
Authors
- Indra Wijaya (ORCID: https://orcid.org/0000-0002-9446-2307)
- Hideru Obinata
- Ajeng Diantini (ORCID: https://orcid.org/0000-0003-2258-5137)
- Melisa Intan Barliana (ORCID: https://orcid.org/0000-0003-0015-9604)
- Ruri Intania
- Nadiya Nurul Afifah
- Lanny Indah Permatasari
Institutions
- Gunma University (JP)
- American Lung Association (US)
- Dr. Hasan Sadikin General Hospital (ID)
- Universitas Esa Unggul (ID)
- Padjadjaran University (ID)
Publication Details
- Journal
- OncoTargets and Therapy
- Published
- 2024-09-01
- DOI
- https://doi.org/10.2147/ott.s475219
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universitas Padjadjaran
- Kementerian Pendidikan, Kebudayaan, Riset, dan Teknologi