Added value of histogram analysis of intravoxel incoherent motion and diffusion kurtosis imaging for the evaluation of complete response to neoadjuvant therapy in locally advanced rectal cancer
Question The current conventional imaging evaluation system lacks adequacy for assessing CR to NAT in LARC. Findings Significantly improved diagnostic performance was observed with the histogram analysis of IVIM and DKI in conjunction with conventional MRI. Clinical relevance IVIM and DKI provide significant value in evaluating CR to NAT in LARC, which bears significant implications for reducing surgical complications and facilitating organ preservation.
Authors
- Fan Yang (ORCID: https://orcid.org/0000-0002-1044-7821)
- Chuansheng Zheng (ORCID: https://orcid.org/0000-0002-2435-1417)
- Xin Li (ORCID: https://orcid.org/0000-0002-7381-1352)
- Ziwei Jin (ORCID: https://orcid.org/0000-0001-8939-9799)
- Kaixiong Tao (ORCID: https://orcid.org/0000-0002-7723-6121)
- Tao Zhang (ORCID: https://orcid.org/0000-0001-6643-4686)
- Peng Sun (ORCID: https://orcid.org/0000-0002-0150-9955)
- Ming Yang (ORCID: https://orcid.org/0000-0001-8671-9750)
- Man Chen (ORCID: https://orcid.org/0009-0006-4599-7328)
- Yuan Liu (ORCID: https://orcid.org/0000-0003-4887-907X)
- Zhenyu Lin (ORCID: https://orcid.org/0000-0002-1733-5806)
- Yiwan Guo
- Si Xu (ORCID: https://orcid.org/0000-0001-9322-8263)
- Peng Zhang (ORCID: https://orcid.org/0009-0004-7146-1805)
- Lan Zhang (ORCID: https://orcid.org/0009-0001-2576-4010)
Institutions
- Union Hospital (HK)
- Philips (Finland) (FI)
- State Key Laboratory of Information Engineering in Surveying Mapping and Remote Sensing (CN)
- Wuhan Union Hospital (CN)
- Union Hospital (CN)
- Huazhong University of Science and Technology (CN)
- Hubei University (CN)
Publication Details
- Journal
- European Radiology
- Published
- 2024-09-19
- DOI
- https://doi.org/10.1007/s00330-024-11081-z
- Citations
- 9
- Primary Topic
- Colorectal Cancer Surgical Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.54
Funders
- National Natural Science Foundation of China
- Sun Yat-sen University