Establishment of cross-priming amplification for point-of-care detection of Mycobacterium tuberculosis and non-tuberculosis mycobacteria
6M GTC can liquefy sputum and render MTB non-viable, eliminating the need for Mycobacterium nucleic acid testing in BSL-2 laboratories; the newly established CPA method can rapidly and accurately distinguish MTB and NTM in the form of POCT, with simple and fast operation, suitable for promotion and application in grassroots medical institutions and remote rural areas.
Authors
- Ting Xiao (ORCID: https://orcid.org/0000-0003-4107-0454)
- Dingchang Wu
- Liping Chen (ORCID: https://orcid.org/0000-0002-5801-7791)
- Wenbin Huang (ORCID: https://orcid.org/0009-0003-0511-9887)
- Yuankui Lin
- M Zhang (ORCID: https://orcid.org/0009-0005-4853-4532)
Institutions
- Fujian Medical University (CN)
- Longyan University (CN)
- Ustar Biotechnologies (China) (CN)
- First Affiliated Hospital of Fujian Medical University (CN)
Publication Details
- Journal
- Heliyon
- Published
- 2024-09-19
- DOI
- https://doi.org/10.1016/j.heliyon.2024.e37930
- Citations
- 3
- Primary Topic
- Mycobacterium research and diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 1.16