Sex differences in ST-segment elevation acute myocardial infarction

Introduction: Acute ST-segment elevation myocardial infarction constitutes a health problem in the world and in Cuba, with differences according to sex in clinical and laboratory findings, complications and therapeutic response. Objective: to identify sex differences in ST-segment elevation myocardial infarction. Methods: quantitative, cross-sectional, retrospective study of 155 patients, 97 men and 58 women, from the Coronary Intensive Care Unit of the Institute of Cardiology and Cardiovascular Surgery, from January 2020-December 2021. The following variables were explored: general, admission, hospitalization and complications. Results: the following were statistically significant: men developed infarction earlier than women (65±13 vs 71±11.9); of the known coronary risk factors, arterial hypertension predominated (61.3%); smoking prevailed in men (53%) and 54% of the patients with an anterior-extensive topographic location died (80% in men and 100% in women). In addition, there was a predominance of Killip-Kimball IV classification (15.5%), right coronary artery as the responsible vessel (29.9%), heart failure as a complication (26.8%) and death (15.5%) in men. However, in women, the anterior descending coronary artery prevailed as the vessel responsible for the lesion (34.4%). Conclusions: there are differences between men and women in age, risk factors and clinical manifestations of ST-segment elevation myocardial infarction. Women were more likely to present extensive anterior myocardial infarction, a topography that had a greater incidence of mortality as a complication