A Real-World Comparison of Drug Trough Levels between Patients Experiencing a Secondary Nonimmune Loss of Response and Those Maintaining a Response to Infliximab on Long-Term Maintenance Therapy for Inflammatory Bowel Disease

Our results did not demonstrate lower IFX levels among patients experiencing secondary nonimmune LOR on long-term therapy. Our results do not redefine the therapeutic IFX goal levels for those patients on long-term therapy and suggest that underdosing of IFX is not the cause of secondary LOR.

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Publication Details

Journal
Inflammatory Intestinal Diseases
Published
2024-09-19
DOI
https://doi.org/10.1159/000541377
Primary Topic
Inflammatory Bowel Disease
Type
article
Field-Weighted Citation Impact
0.00

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article

A Real-World Comparison of Drug Trough Levels between Patients Experiencing a Secondary Nonimmune Loss of Response and Those Maintaining a Response to Infliximab on Long-Term Maintenance Therapy for Inflammatory Bowel Disease

Nina Kohn, Arun Swaminath, Jeremy Polman, Keith Sultan et al.
Inflammatory Intestinal Diseases
Inflammatory Bowel Disease
article

A Real-World Comparison of Drug Trough Levels between Patients Experiencing a Secondary Nonimmune Loss of Response and Those Maintaining a Response to Infliximab on Long-Term Maintenance Therapy for Inflammatory Bowel Disease

Nina Kohn, Arun Swaminath, Jeremy Polman, Keith Sultan, Michael Färber, Vincent Chua
article en

Abstract

Our results did not demonstrate lower IFX levels among patients experiencing secondary nonimmune LOR on long-term therapy. Our results do not redefine the therapeutic IFX goal levels for those patients on long-term therapy and suggest that underdosing of IFX is not the cause of secondary LOR.

Inflammatory Intestinal DiseasesVol. 9(1)
Northwell Health (US), North Shore University Hospital (US), Lenox Hill Hospital (US), New York Institute of Technology (US)
Northwell Health
Openalex Percentile: Top 82%
Inflammatory Bowel Disease
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A Real-World Comparison of Drug Trough Levels between Patients Experiencing a Secondary Nonimmune Loss of Response and Those Maintaining a Response to Infliximab on Long-Term Maintenance Therapy for Inflammatory Bowel Disease — Nina Kohn, Arun Swaminath, et al. · Inflammatory Intestinal Diseases (2024) | TGRS Research Map | TGRS