Unveiling the Enigma of Statin-Induced Necrotizing Autoimmune Myopathy: A Comprehensive Case Analysis and Pathogenic Insights
Statins are widely prescribed to patients for their efficiency in cholesterol management. However, they carry the risk of inducing a relatively rare, serious, and potentially life-threatening condition known as statin-induced necrotizing autoimmune myopathy (SINAM). This case report provides an in-depth analysis of SINAM, focusing on its epidemiology, clinical presentation, and the challenges involved in accurate diagnosis. In addition, we review evolving theories addressing its pathogenesis and current therapeutic approaches. This report identifies the need for early diagnosis and intervention and recommends a multidisciplinary approach to optimize patient outcomes. This article also highlights the need for further research studies to enhance our understanding of SINAM and its management.
Authors
- Swati Baraiya
- Praneeth Ulavala
- Hari Chandana Kalangi
- Hemalatha Bhoompally
- Abhishek Vadher
Institutions
- North Shore University Hospital (US)
- North Shore Hospital (NZ)
- Kamineni Hospitals (IN)
- Yashoda Hospital (IN)
- Bombay Hospital (IN)
- Narayan Medical College and Hospital (IN)
Publication Details
- Journal
- Cureus
- Published
- 2024-09-19
- DOI
- https://doi.org/10.7759/cureus.69751
- Primary Topic
- Inflammatory Myopathies and Dermatomyositis
- Type
- article
- Field-Weighted Citation Impact
- 0.00